Abstract
Apnea in a premature infant is not always due to immaturity and caffeine is not always the answer. We report a case of apnea in a preterm infant who presented at two weeks of life with increase in frequency of apnea that did not respond to caffeine. Family history was significant for diarrhea in a sibling. Stool PCR was positive for Norovirus Genogroup II. Enteric isolation was instituted and the apnea resolved spontaneously with conservative management. Re-emergence of apnea or persistent apnea necessitates further investigation to elucidate the etiology.
MeSH terms
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Antiviral Agents / therapeutic use
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Apnea / drug therapy
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Apnea / etiology*
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DNA, Viral / analysis
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Enzyme-Linked Immunosorbent Assay
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Female
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Follow-Up Studies
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Gastroenteritis / complications*
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Gastroenteritis / diagnosis
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Gastroenteritis / drug therapy
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Gastroenteritis / virology*
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Gestational Age
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Humans
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Infant, Newborn
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Infant, Premature*
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Intensive Care Units, Neonatal
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Male
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Norovirus / isolation & purification*
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Pregnancy
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Reverse Transcriptase Polymerase Chain Reaction
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Risk Assessment
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Severity of Illness Index
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Treatment Outcome
Substances
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Antiviral Agents
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DNA, Viral