Serious adverse reactions in a tuberculosis programme setting in Kyrgyzstan

Int J Tuberc Lung Dis. 2009 Dec;13(12):1560-2.

Abstract

Serious adverse reactions among new smear-positive patients were studied in a programme setting in Kyrgyzstan. Two per cent of patients on tuberculosis (TB) treatment had to interrupt treatment for > or =1 week, and more than 80% of the reactions occurred during the first month of treatment. Pyrazinamide was the most common causative agent, followed by rifampicin.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Adult
  • Antitubercular Agents / adverse effects*
  • Antitubercular Agents / therapeutic use
  • Communicable Disease Control / methods
  • Humans
  • Kyrgyzstan / epidemiology
  • Pyrazinamide / adverse effects
  • Pyrazinamide / therapeutic use
  • Rifampin / adverse effects
  • Rifampin / therapeutic use
  • Sputum / microbiology
  • Tuberculosis / drug therapy*

Substances

  • Antitubercular Agents
  • Pyrazinamide
  • Rifampin