Multiscale simulation of protein mediated membrane remodeling

Gary S Ayton; Gregory A Voth

doi:10.1016/j.semcdb.2009.11.011

Multiscale simulation of protein mediated membrane remodeling

Semin Cell Dev Biol. 2010 Jun;21(4):357-62. doi: 10.1016/j.semcdb.2009.11.011. Epub 2009 Nov 13.

Authors

Gary S Ayton¹, Gregory A Voth

Affiliation

¹ Center for Biophysical Modeling and Simulation and Department of Chemistry, University of Utah, Salt Lake City, UT 84112-0850, USA.

Abstract

Proteins interacting with membranes can result in substantial membrane deformations and curvatures. This effect is known in its broadest terms as membrane remodeling. This review article will survey current multiscale simulation methodologies that have been employed to examine protein mediated membrane remodeling.

Publication types

Research Support, N.I.H., Extramural
Review

MeSH terms

Cell Membrane* / chemistry
Cell Membrane* / ultrastructure
Computer Simulation*
Models, Molecular*
Protein Conformation
Proteins* / chemistry
Proteins* / metabolism

Substances

Proteins

Abstract

Publication types

MeSH terms

Substances

Grants and funding