A pilot study of hereditary breast and ovarian knowledge among a multiethnic group of Hispanic women with a personal or family history of cancer

Genet Test Mol Biomarkers. 2010 Feb;14(1):99-106. doi: 10.1089/gtmb.2009.0088.

Abstract

Purpose: To examine knowledge about hereditary breast and ovarian cancer (HBOC) among Mexican, Puerto Rican, and Cuban women.

Methods: Women (age range, 18-65 years) with a personal or family history of breast or ovarian cancer were recruited to a mixed methods study using community-based approaches. Fifty-three women participated in the study: 16 Mexicans, 20 Puerto Ricans, and 17 Cubans. The majority of women (64.2%) were born outside the United States. All questions were interviewer administered in Spanish or English. HBOC knowledge was measured using an 11-item instrument developed by the National Center for Human Genome Research. We evaluated whether differences in knowledge varied as a function of Hispanic subethnicity, demographic characteristics, and medical and acculturation characteristics using a series of one-way analysis of variances.

Results: The percentage of correct responses on the knowledge instrument ranged from 9.4% to 73.6% (median number of correct responses = 45%). Knowledge did not significantly differ by Hispanic subethnicity (p = 0.51). Exploratory analysis revealed lower knowledge in women with a personal history of cancer (p = 0.03).

Conclusion: Our study provides important information about characteristics associated with lower levels of knowledge and specific areas related to HBOC where additional education may be warranted in the Hispanic community.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Breast Neoplasms / genetics*
  • Breast Neoplasms / psychology*
  • Cross-Sectional Studies
  • Cuba / ethnology
  • Female
  • Genes, BRCA1
  • Genes, BRCA2
  • Health Knowledge, Attitudes, Practice*
  • Hispanic or Latino / genetics*
  • Hispanic or Latino / psychology*
  • Humans
  • Language
  • Mexican Americans / genetics
  • Mexican Americans / psychology
  • Middle Aged
  • Ovarian Neoplasms / genetics*
  • Ovarian Neoplasms / psychology*
  • Pilot Projects
  • Puerto Rico / ethnology
  • Surveys and Questionnaires
  • Young Adult