Abstract
When fever occurs in a patient treated with a neuroleptic, the diagnosis of a neuroleptic malignant syndrome is difficult to differentiate to that of an infectious event. Among inflammation biomarkers of inflammation, serum procalcitonin levels increase both quickly and specifically during a bacterial infection. We report the first case of a neuroleptic malignant syndrome associated with a significant increase of serum procalcitonin levels, without concomitant septic syndrome. The neuroleptic malignant syndrome might be a non-infectious clinical situation associated with an increased serum procalcitonin concentration.
MeSH terms
-
Aged, 80 and over
-
Analgesics, Non-Narcotic / administration & dosage
-
Analgesics, Non-Narcotic / therapeutic use
-
Antipsychotic Agents / therapeutic use
-
Body Temperature
-
C-Reactive Protein / metabolism
-
Calcitonin / blood*
-
Calcitonin Gene-Related Peptide
-
Diagnosis, Differential
-
Female
-
Fluid Therapy
-
Hallucinations / etiology
-
Haloperidol / therapeutic use
-
Humans
-
Inflammation / blood
-
Inflammation / etiology
-
Neuroleptic Malignant Syndrome / blood*
-
Neuroleptic Malignant Syndrome / diagnosis
-
Neuroleptic Malignant Syndrome / therapy
-
Protein Precursors / blood*
-
Psychotic Disorders / etiology*
-
Treatment Outcome
Substances
-
Analgesics, Non-Narcotic
-
Antipsychotic Agents
-
CALCA protein, human
-
Protein Precursors
-
Calcitonin
-
C-Reactive Protein
-
Haloperidol
-
Calcitonin Gene-Related Peptide