Race moderates the relationship between obesity and colorectal cancer screening in women

Cancer Causes Control. 2010 Mar;21(3):373-85. doi: 10.1007/s10552-009-9469-x. Epub 2009 Nov 26.

Abstract

Objective: To determine if the relationship between obesity and usage of colorectal cancer (CRC) screening in women varies when stratifying by race.

Methods: Using nationally representative data from the 2005 National Health Interview Survey, we examined the relationship between obesity and CRC screening for white and African-American women aged 50 and older. Screening usage variables indicated if a woman was up-to-date for any CRC screening test, colonoscopy, or FOBT. We used multivariable logistic regression models that included interaction terms to determine if race moderates the obesity-screening relationship. We also calculated adjusted up-to-date colonoscopy rates using direct standardization to model covariates.

Results: The relationship between obesity and screening differed by race for any CRC screening test (P = 0.04 for interaction) and for colonoscopy (P = 0.01 for interaction), but not for FOBT. Obese white women had a lower adjusted colonoscopy rate (30.2%, 95% CI 25.9-34.8) than non-obese white women (39.1%, 95% CI 36.1-42.2). Obese African-American women, on the other hand, had a higher adjusted colonoscopy rate (41.2%, 95% CI 31.6-51.4) than their non-obese counterparts (35.6%, 95% CI 28.3-43.6). Overall, adjusted colonoscopy rates were lowest among obese white women.

Conclusions: Obesity is associated with lower CRC screening rates in white, but not African-American women.

Publication types

  • Comparative Study
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Black or African American / statistics & numerical data*
  • Body Mass Index
  • Colonoscopy / statistics & numerical data
  • Colorectal Neoplasms / diagnosis
  • Colorectal Neoplasms / epidemiology*
  • Comorbidity
  • Confidence Intervals
  • Female
  • Humans
  • Mass Screening / statistics & numerical data*
  • Middle Aged
  • Obesity / epidemiology*
  • Odds Ratio
  • Patient Acceptance of Health Care / statistics & numerical data*
  • Sigmoidoscopy / statistics & numerical data
  • Socioeconomic Factors
  • United States / epidemiology
  • White People / statistics & numerical data*
  • Women's Health