[Hepatitis A virus detection in shellfish from Tunisia by reverse transcription-nested PCR--investigation of a correlation between viral and bacterial contamination]

Pathol Biol (Paris). 2011 Aug;59(4):217-21. doi: 10.1016/j.patbio.2009.10.009. Epub 2009 Nov 26.
[Article in French]

Abstract

Objectives: We aimed at evaluating the contamination by hepatitis A virus (HAV) of 54 shellfish samples collected from five Tunisian shellfish harvesting areas and finding a correlation between bacterial and viral contamination.

Material and methods: Fifty-four shellfish samples were analysed in our study. Two methods of viral extraction were evaluated by reverse transcription-nested PCR. The first one was based on elution by glycine solution and the second one used a beef extract solution. Bacteriological determination (Samonella and E. coli) was carried out for all shellfish samples.

Results: Glycine extraction showed a higher detection rate of HAV compared to the saline beef extraction method. The hepatitis A virus was detected in 32 % of shellfish samples analysed. None of the samples revealed the presence of Samonella. From 17 samples positive for HAV, we found six samples showing a number of E. coli below the European legislation.

Conclusion: An important HAV contamination was observed in our study. No correlation between bacterial and viral contamination was found.

Publication types

  • Comparative Study

MeSH terms

  • Animals
  • Bacteria / isolation & purification*
  • DNA, Bacterial / analysis
  • DNA, Viral / analysis
  • Escherichia coli / genetics
  • Escherichia coli / isolation & purification
  • Food Microbiology / methods*
  • Hepatitis A virus / genetics
  • Hepatitis A virus / isolation & purification*
  • Reverse Transcriptase Polymerase Chain Reaction*
  • Salmonella / genetics
  • Salmonella / isolation & purification
  • Shellfish / virology*
  • Tunisia

Substances

  • DNA, Bacterial
  • DNA, Viral