Abstract
We identified febrile pediatric outpatients seeking care for influenza like illness in Bangkok. Two nasal and 1 throat swab were tested using the QuickVue A+B rapid influenza kit and reverse transcription-polymerase chain reaction. Among 142 pandemic influenza A (H1N1)-positive patients, the QuickVue test identified 89 positive tests for a sensitivity of 62.7% (95% confidence interval [CI]: 54.7-70.6). Specificity was 99.2% (95% CI: 98-100). In the 0 to 2 years age group, sensitivity was 76.7% (95% CI: 61.5-91.8). Throat and nasal swabs are equally useful diagnostic specimens for reverse transcription-polymerase chain reaction diagnosis.
Publication types
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Comparative Study
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Evaluation Study
MeSH terms
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Adolescent
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Antigens, Viral / analysis
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Child
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Child, Preschool
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Disease Outbreaks
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Humans
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Immunoassay / methods
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Infant
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Infant, Newborn
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Influenza A Virus, H1N1 Subtype / genetics
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Influenza A Virus, H1N1 Subtype / immunology
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Influenza A Virus, H1N1 Subtype / isolation & purification*
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Influenza A virus / immunology
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Influenza A virus / isolation & purification
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Influenza B virus / immunology
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Influenza B virus / isolation & purification
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Influenza, Human / diagnosis*
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Influenza, Human / virology
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Nose / virology*
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Pharynx / virology*
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RNA, Viral / analysis
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RNA, Viral / isolation & purification
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Reagent Kits, Diagnostic*
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Reverse Transcriptase Polymerase Chain Reaction
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Sensitivity and Specificity
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Specimen Handling / methods
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Thailand
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Time Factors
Substances
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Antigens, Viral
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RNA, Viral
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Reagent Kits, Diagnostic