Abstract
A booster dose of Haemophilus influenzae type b-Neisseria meningitidis serogroup C conjugate (Hib-MenC-TT) vaccine simultaneously administered with measles, mumps, and rubella (MMR) vaccine in 13- to 14-month-old Spanish toddlers, primed with 3 doses of a combined Diphteria-Tetanus-Acellular Pertusis DTPa-Hib-containing vaccine and a MenC-CRM197 conjugate vaccine, had a good reactogenicity profile and induced similar Hib and MenC booster responses and MMR seropositivity rates as the vaccines given alone.
Trial registration:
ClinicalTrials.gov NCT00263653.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antibodies, Bacterial / blood
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Antibodies, Viral / blood
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Drug-Related Side Effects and Adverse Reactions
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Female
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Haemophilus Vaccines / adverse effects*
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Haemophilus Vaccines / immunology*
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Humans
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Immunization, Secondary / adverse effects*
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Immunization, Secondary / methods
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Infant
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Male
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Measles-Mumps-Rubella Vaccine / adverse effects*
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Measles-Mumps-Rubella Vaccine / immunology*
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Meningococcal Vaccines / adverse effects*
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Meningococcal Vaccines / immunology*
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Spain
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Tetanus Toxoid / adverse effects*
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Tetanus Toxoid / immunology*
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Vaccines, Combined / adverse effects
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Vaccines, Combined / immunology
Substances
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Antibodies, Bacterial
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Antibodies, Viral
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Haemophilus Vaccines
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Haemophilus influenza type b polysaccharide vaccine-tetanus toxin conjugate
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Measles-Mumps-Rubella Vaccine
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Meningococcal Vaccines
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Tetanus Toxoid
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Vaccines, Combined
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serogroup C meningococcal conjugate vaccine
Associated data
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ClinicalTrials.gov/NCT00263653