[Cutaneous lymphomas]

Rev Prat. 2009 Nov 20;59(9):1207-15.
[Article in French]

Abstract

Cutaneous lymphomas are lymphoproliferations affecting skin only at the time of diagnosis. There are two major types, B-cell lymphomas and T-cell lymphomas, which prognosis depends of histological subtype and staging evaluation. In cutaneous B-cell lymphomas, there are two indolent subtypes (primary cutaneous marginal zone B-cell lymphoma and primary cutaneous follicle center lymphoma) and one more aggressive type (primary cutaneous diffuse large B-cell lymphoma, leg type). Classification of T-cell lymphomas distinguishes indolent subtypes such as mycosis fungoides, the most frequent of T-cell lymphomas, and CD30+ lymphoproliferations such as lymphomatoid papulosis, whereas other T-cell lymphoma subtypes have a more pejorative prognosis such as Sezary syndrome (erythrodermic and leukemic form of mycosis fungoides) and CD30- lymphomas. Staging evaluation with CT-scan of chest, abdomen and pelvis, bone marrow examination if necessary and lymph node biopsy if palpable node over 1 or 1.5 cm diameter, is necessary for therapeutic decision.

Publication types

  • Comparative Study
  • Review

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Humans
  • Immunohistochemistry
  • Lymphoma* / pathology
  • Lymphoma, B-Cell / diagnosis
  • Lymphoma, B-Cell / diagnostic imaging
  • Lymphoma, B-Cell / drug therapy
  • Lymphoma, B-Cell / pathology
  • Lymphoma, B-Cell / radiotherapy
  • Lymphoma, B-Cell / surgery
  • Lymphoma, T-Cell / diagnosis
  • Lymphoma, T-Cell / diagnostic imaging
  • Lymphoma, T-Cell / drug therapy
  • Lymphoma, T-Cell / pathology
  • Lymphoma, T-Cell / radiotherapy
  • Lymphoma, T-Cell / surgery
  • Mycosis Fungoides / diagnosis
  • Mycosis Fungoides / diagnostic imaging
  • Neoplasm Staging
  • Prognosis
  • Radiography, Abdominal
  • Radiography, Thoracic
  • Sezary Syndrome / diagnosis
  • Sezary Syndrome / diagnostic imaging
  • Sezary Syndrome / pathology
  • Skin / pathology
  • Skin Neoplasms* / diagnosis
  • Skin Neoplasms* / diagnostic imaging
  • Skin Neoplasms* / drug therapy
  • Skin Neoplasms* / pathology
  • Skin Neoplasms* / radiotherapy
  • Skin Neoplasms* / surgery
  • Tomography, X-Ray Computed