[Cardiac surgery in an octogenarian with idiopathic thrombocytopenic purpura: report of a case]

Kyobu Geka. 2009 Dec;62(13):1178-81.
[Article in Japanese]

Abstract

An 81-year-old woman was referred to our hospital for surgical treatment for mitral valve regurgitation, tricuspid valve regurgitation and atrial fibrillatory bradycardia. The platelet count on admission was 4.9 x 10(4)/microl. and the results of other studies were compatible with idiopathic thrombocytopenic purpura. Although we performed high-dose transvenous immunoglobulin infusion (400 mg/kg/day) for 5 consecutive days, the platelet count showed no remarkable change. Because of progression of heart failure, we underwent cardiac operation under thrombocytopenic condition. Intra and post-operative platelet transfusion might contribute to postoperative course uneventful without bleeding tendency. In this case, high-dose immunoglobulin therapy was not effective. However the operative course was satisfactory with adequate surgical hemostasis and platelet transfusion.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Aged, 80 and over
  • Atrial Fibrillation / surgery
  • Female
  • Heart Valve Prosthesis*
  • Humans
  • Immunoglobulins, Intravenous / therapeutic use
  • Mitral Valve Insufficiency / surgery
  • Pacemaker, Artificial*
  • Prosthesis Implantation*
  • Purpura, Thrombocytopenic, Idiopathic / complications*
  • Purpura, Thrombocytopenic, Idiopathic / drug therapy
  • Tricuspid Valve Insufficiency / surgery

Substances

  • Immunoglobulins, Intravenous