Influence of patient age on the association between euploidy and day-3 embryo morphology

Jennifer L Eaton; Michele R Hacker; C Brent Barrett; Kim L Thornton; Alan S Penzias

doi:10.1016/j.fertnstert.2009.09.019

Influence of patient age on the association between euploidy and day-3 embryo morphology

Fertil Steril. 2010 Jun;94(1):365-7. doi: 10.1016/j.fertnstert.2009.09.019. Epub 2009 Dec 14.

Authors

Jennifer L Eaton¹, Michele R Hacker, C Brent Barrett, Kim L Thornton, Alan S Penzias

Affiliation

¹ Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.

PMID: 20004892
DOI: 10.1016/j.fertnstert.2009.09.019

Abstract

A retrospective cohort study conducted in 138 patients undergoing their first preimplantation genetic screening (PGS) cycle between January 1, 2006, and December 31, 2007, demonstrated that embryos with good day-3 morphology were more likely to be euploid for X/Y, 8, 15, and 18 than those with poor morphology. The strength of association between euploidy and day-3 morphology was not influenced by maternal age.

Publication types

Comparative Study
Letter

MeSH terms

Adult
Age Factors
Cohort Studies
Embryo Implantation / physiology
Embryo Transfer / methods
Embryonic Development* / physiology
Female
Humans
Maternal Age*
Ploidies*
Pregnancy
Preimplantation Diagnosis* / methods
Retrospective Studies