Ranibizumab for coloboma-related choroidal neovascular membrane in a child

Peter Goodwin; Carol L Shields; Aparna Ramasubramanian; Gary C Brown; Jerry A Shields

doi:10.1016/j.jaapos.2009.09.009

Ranibizumab for coloboma-related choroidal neovascular membrane in a child

J AAPOS. 2009 Dec;13(6):616-7. doi: 10.1016/j.jaapos.2009.09.009.

Authors

Peter Goodwin¹, Carol L Shields, Aparna Ramasubramanian, Gary C Brown, Jerry A Shields

Affiliation

¹ Ocular Oncology, Wills Eye Institute, Thomas Jefferson University, 840 Walnut Street, Philadelphia, PA 19107, USA.

PMID: 20006832
DOI: 10.1016/j.jaapos.2009.09.009

Abstract

Optic nerve and retinochoroidal coloboma are caused by incomplete closure of the embryonic fissure during fetal development.(1) Affected patients carry a risk for retinal detachment and less so for choroidal neovascular membranes (CNVM) secondary to the altered anatomy. Because of the rarity of this condition and the even more unusual occurrence of such complications, there are only a few case reports on the treatment of coloboma-related CNVM. Herein we report the results of ranibizumab and laser photocoagulation for coloboma-related CNVM in a child.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Antibodies, Monoclonal / therapeutic use*
Antibodies, Monoclonal, Humanized
Choroid / abnormalities*
Choroidal Neovascularization / diagnosis
Choroidal Neovascularization / etiology
Choroidal Neovascularization / therapy*
Coloboma / complications*
Combined Modality Therapy
Fluorescein Angiography
Humans
Infant
Injections
Laser Coagulation*
Male
Prognosis
Ranibizumab
Retina / abnormalities*
Retreatment
Vitreous Body

Substances

Antibodies, Monoclonal
Antibodies, Monoclonal, Humanized
Ranibizumab