Abstract
A case of enterococcal meningitis in a toddler is presented. The organism was highly resistant to all drugs previously used for pediatric Gram-positive meningitis. She was successfully treated with intraventricular and intravenous daptomycin and intravenous tigecycline. The organism was characterized as a member of CC17, a notorious emerging nosocomial clone of Enterococcus faecium.
Publication types
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Case Reports
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Research Support, N.I.H., Extramural
MeSH terms
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Anti-Bacterial Agents* / administration & dosage
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Anti-Bacterial Agents* / therapeutic use
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Daptomycin* / administration & dosage
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Daptomycin* / therapeutic use
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Drug Resistance, Multiple, Bacterial*
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Enterococcus faecium* / classification
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Enterococcus faecium* / drug effects
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Enterococcus faecium* / isolation & purification
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Female
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Humans
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Infant
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Injections, Intravenous
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Injections, Intraventricular
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Meningitis, Bacterial* / drug therapy
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Meningitis, Bacterial* / microbiology
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Minocycline / administration & dosage
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Minocycline / analogs & derivatives*
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Minocycline / therapeutic use
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Tigecycline
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Treatment Outcome
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Vancomycin Resistance
Substances
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Anti-Bacterial Agents
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Tigecycline
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Minocycline
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Daptomycin