Idiopathic membranous nephropathy associated with polycystic kidney disease

Pediatr Nephrol. 2010 May;25(5):961-3. doi: 10.1007/s00467-009-1398-0. Epub 2009 Dec 22.

Abstract

Membranous nephropathy (MN) and polycystic kidney disease are both relatively rare diseases in children. On rare exceptions, these two conditions have been associated in adults. We report here the first case of a pediatric patient with this association. This 6-year-old child presented with gross hematuria, nephrotic syndrome, and mild renal failure. A renal ultrasound subsequently revealed that the patient also had polycystic kidney disease.

Publication types

  • Case Reports

MeSH terms

  • Biopsy
  • Child
  • Cyclosporine / therapeutic use
  • Drug Therapy, Combination
  • Glomerulonephritis, Membranous / complications*
  • Glomerulonephritis, Membranous / diagnosis
  • Glomerulonephritis, Membranous / drug therapy
  • Hematuria / etiology
  • Humans
  • Immunosuppressive Agents / therapeutic use
  • Kidney / pathology
  • Male
  • Nephrotic Syndrome / etiology
  • Polycystic Kidney Diseases / complications*
  • Polycystic Kidney Diseases / diagnosis
  • Polycystic Kidney Diseases / drug therapy
  • Prednisone / therapeutic use
  • Renal Insufficiency / etiology
  • Severity of Illness Index
  • Treatment Outcome

Substances

  • Immunosuppressive Agents
  • Cyclosporine
  • Prednisone