[Diffusion-weighted MR imaging for postoperative nodal recurrence of esophageal squamous cell cancer in comparison with FDG-PET]

Gan To Kagaku Ryoho. 2009 Nov;36(12):2468-70.
[Article in Japanese]

Abstract

We evaluated the power of DWIBS in patients with postoperative lymph node recurrence of esophageal cancer and compared with FDG-PET findings. Forty-seven suspected lesions by MDCT were enrolled. No significant difference between DWIBS and PET was observed in sensitivity (95% vs 97%), PPV (83% vs 90%) and overall accuracy rate (81% vs 87%). The ADCs (x10(-3) mm2/s) of recurrent nodes, primary cancer and normal esophagus were 1.124, 1.058 and 2.079, respectively. ADCs of recurrent nodes were significantly lower than those of normal esophagus (p<0.0001). The cut-off ADC line of 1.5 revealed 100% overall accuracy for separating the recurrent lesion from normal esophagus. Noninvasive DWIBS may become a valid modality to discriminate nodal recurrence of esophageal cancer by no means inferior to PET.

Publication types

  • Comparative Study
  • English Abstract

MeSH terms

  • Diffusion Magnetic Resonance Imaging* / methods
  • Esophageal Neoplasms / pathology
  • Esophageal Neoplasms / surgery*
  • Humans
  • Lymph Nodes / pathology*
  • Lymphatic Metastasis / diagnosis*
  • Neoplasm Recurrence, Local
  • Positron-Emission Tomography*
  • Sensitivity and Specificity