Localization of monocyte chemotactic protein-1 gene (SCYA2) to human chromosome 17q11.2-q21.1

Genomics. 1991 Jan;9(1):200-3. doi: 10.1016/0888-7543(91)90239-b.

Abstract

Monocyte chemotactic protein-1 (MCP-1) is a member of the small inducible gene (SIG) family. It has been shown to play a role in the recruitment of monocytes to sites of injury and infection. By analysis of a panel of somatic cell hybrids, we have localized the MCP-1 gene, designated SCYA2, to human chromosome 17. In situ hybridization confirmed this assignment and further localized the gene to 17q11.2-q21.1.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Base Sequence
  • Chemokine CCL2
  • Chemotactic Factors / genetics*
  • Chromosome Banding
  • Chromosome Mapping
  • Chromosomes, Human, Pair 17*
  • Genes
  • Humans
  • Hybrid Cells
  • Mice
  • Molecular Sequence Data
  • Monocytes

Substances

  • Chemokine CCL2
  • Chemotactic Factors