Mapping of the gene for human cysteine proteinase inhibitor stefin A, STF1, to chromosome 3cen-q21

Genomics. 1991 Jan;9(1):207-9. doi: 10.1016/0888-7543(91)90241-6.

Abstract

The gene for the human cysteine proteinase inhibitor stefin A (STF1), alias cystatin A, has been mapped to chromosome 3, using the polymerase chain reaction to specifically amplify the human stefin A sequence in human-hamster hybrid DNA. STF1 is further sublocalized to regions between centromere and 3q21 using a deletion mapping panel for this chromosome. This assignment shows that stefin A is not syntenic with cystatin C which has been localized to chromosome 20.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Base Sequence
  • Chromosome Mapping
  • Chromosomes, Human, Pair 3*
  • Cricetinae
  • Cystatin A
  • Cystatins / genetics*
  • Cysteine Proteinase Inhibitors*
  • Humans
  • Hybrid Cells
  • Molecular Sequence Data
  • Polymerase Chain Reaction

Substances

  • Cystatin A
  • Cystatins
  • Cysteine Proteinase Inhibitors
  • CSTA protein, human