Adrenal insufficiency in newborns with congenital diaphragmatic hernia

J Pediatr. 2010 Mar;156(3):495-497.e1. doi: 10.1016/j.jpeds.2009.10.044. Epub 2010 Jan 13.

Abstract

Newborns with congenital diaphragmatic hernia frequently have catecholamine-unresponsive systemic hypotension and respiratory failure. We found that adrenal insufficiency frequently complicates the clinical course of infants with congenital diaphragmatic hernia and was associated with increased severity of illness.

MeSH terms

  • Adrenal Insufficiency / complications*
  • Adrenal Insufficiency / congenital*
  • Adrenal Insufficiency / diagnosis
  • Adrenal Insufficiency / drug therapy
  • Biomarkers / blood
  • Hernia, Diaphragmatic / complications*
  • Hernias, Diaphragmatic, Congenital*
  • Humans
  • Hydrocortisone / blood
  • Infant, Newborn

Substances

  • Biomarkers
  • Hydrocortisone