Domperidone-induced acute dystonia and polycystic ovary syndrome

Mov Disord. 1991;6(1):79-81. doi: 10.1002/mds.870060116.

Abstract

The occurrence of acute dystonic reactions (ADRs) due to domperidone administration in two young women is reported. In both patients, a typical polycystic ovary (PCO) syndrome was found. The possibility that the relative hyperestrogenism typical of PCO syndrome acted as a facilitating factor for ADR is discussed.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adolescent
  • Adult
  • Domperidone / administration & dosage
  • Domperidone / adverse effects*
  • Dyskinesia, Drug-Induced / blood
  • Dyskinesia, Drug-Induced / etiology*
  • Dystonia / blood
  • Dystonia / chemically induced*
  • Estrogens / blood
  • Female
  • Humans
  • Nausea / blood
  • Nausea / drug therapy*
  • Polycystic Ovary Syndrome / blood
  • Polycystic Ovary Syndrome / complications*
  • Vomiting / blood
  • Vomiting / drug therapy*

Substances

  • Estrogens
  • Domperidone