[Prognostic factors and comorbidity impact upon the frontolateral laryngectomy]

Rev Col Bras Cir. 2009 Oct;36(5):392-7. doi: 10.1590/s0100-69912009000500006.
[Article in Portuguese]

Abstract

Objective: To evaluate the survival rates, comorbidity impact, complications, and treatment failure facts.

Methods: 38 patients clinically staged as T1b / T2N0M0 glottic tumors were analyzed. They underwent frontolateral laryngectomy with reconstruction, from January, 1995 to December, 2006. The oncological outcome, comorbidity (through the Adult Comorbidity Evaluation -27 ACE-27 scale) and complications were studied and correlated to the demographic data and tumor characteristics.

Results: Eight patients presented local recurrence being surgically salvaged. Complications were not observed in 33 patients. There was no significant difference on the global and free of disease 5-year survival regarding the diverse comorbidity categories. Only the pathological margins spread of the tumor presented significant difference on the global (p=0.0033) and free of disease survival (p<0.0001).

Conclusion: The 5-year global survival was 67.6% whereas the free of disease survival was 73.7%; the comorbidity did not represent independent prognostic factor; the postoperative complications rate was 13.2%; and only the pathological margin spread showed significant difference on the global and free of disease survival rates.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Female
  • Glottis*
  • Humans
  • Laryngeal Neoplasms / complications
  • Laryngeal Neoplasms / surgery*
  • Laryngectomy / adverse effects*
  • Laryngectomy / methods*
  • Male
  • Middle Aged
  • Neoplasm Recurrence, Local / epidemiology
  • Postoperative Complications / epidemiology
  • Prognosis