Fetal radiation exposure and moyamoya disease

J Clin Neurosci. 2010 Mar;17(3):406-7. doi: 10.1016/j.jocn.2009.06.032. Epub 2010 Jan 20.

Abstract

Moyamoya disease is a progressive occlusive disease of the cerebral vasculature with particular involvement of the circle of Willis. We present the first reported patient with moyamoya disease possibly due to radiation exposure during fetal development. A 10-year-old male, whose mother had undergone radiotherapy when pregnant, presented with moyamoya disease. The relevant literature is discussed.

Publication types

  • Case Reports

MeSH terms

  • Brain Infarction / etiology
  • Child
  • Coronary Angiography / methods
  • Female
  • Humans
  • Male
  • Moyamoya Disease / etiology*
  • Paresis / complications
  • Pregnancy
  • Prenatal Exposure Delayed Effects*
  • Radiotherapy / adverse effects*
  • Tomography, X-Ray Computed / methods