Endometrial stromal progesterone receptor-A/progesterone receptor-B ratio: no difference between women with and without endometriosis

Fertil Steril. 2010 Sep;94(4):1538-1540. doi: 10.1016/j.fertnstert.2009.12.018. Epub 2010 Jan 25.

Abstract

The aim of the present study was to investigate whether alterations of the P receptor-A/P receptor-B ratio could be considered an etiopathogenetic factor for endometriosis. We failed to observe statistically significant differences in both P receptor-A/P receptor-B messenger RNA and protein ratio between endometrial stromal cells derived from women with and without endometriosis.

MeSH terms

  • Case-Control Studies
  • Endometriosis / genetics*
  • Endometriosis / metabolism
  • Endometriosis / pathology
  • Endometrium / metabolism*
  • Endometrium / pathology
  • Estradiol / metabolism
  • Female
  • Gene Expression Regulation / physiology
  • Humans
  • Menstrual Cycle / genetics
  • Menstrual Cycle / metabolism
  • Menstrual Cycle / physiology
  • RNA, Messenger / analysis
  • RNA, Messenger / metabolism
  • Receptors, Progesterone / analysis
  • Receptors, Progesterone / genetics*
  • Receptors, Progesterone / metabolism
  • Stromal Cells / metabolism
  • Stromal Cells / pathology
  • Uterine Diseases / genetics*
  • Uterine Diseases / metabolism
  • Uterine Diseases / pathology

Substances

  • RNA, Messenger
  • Receptors, Progesterone
  • progesterone receptor A
  • progesterone receptor B
  • Estradiol