Bone: adiposity and bone accrual-still an established paradigm?

Masanobu Kawai; Clifford J Rosen

doi:10.1038/nrendo.2009.249

Bone: adiposity and bone accrual-still an established paradigm?

Nat Rev Endocrinol. 2010 Feb;6(2):63-4. doi: 10.1038/nrendo.2009.249.

Authors

Masanobu Kawai¹, Clifford J Rosen

Affiliation

¹ Skeletal Research Laboratory, Maine Medical Center Research Institute, 81 Research Drive, Scarborough, ME 04074-7205, USA.

PMID: 20098443
DOI: 10.1038/nrendo.2009.249

Abstract

The paradigm that obesity at any age is protective against skeletal failure has been ingrained in clinical practice for several decades. A new study published in the Journal of Bone and Mineral Research challenges the basic framework of that tenet.

MeSH terms

Adiposity*
Adolescent
Adult
Bone Density
Child
Female
Fractures, Bone / epidemiology
Humans
Male
Obesity / complications
Osteogenesis*
Osteoporosis, Postmenopausal
Risk Factors