An unusual case of an aldosterone-producing adrenocortical adenoma presenting with rhabdomyolysis

Gülay Karagüzel; Elif Bahat; Mustafa Imamoğlu; Ali Ahmetoğlu; Kadriye Yildiz; Ayşenur Okten

doi:10.1515/jpem.2009.22.11.1087

An unusual case of an aldosterone-producing adrenocortical adenoma presenting with rhabdomyolysis

J Pediatr Endocrinol Metab. 2009 Nov;22(11):1087-90. doi: 10.1515/jpem.2009.22.11.1087.

Authors

Gülay Karagüzel¹, Elif Bahat, Mustafa Imamoğlu, Ali Ahmetoğlu, Kadriye Yildiz, Ayşenur Okten

Affiliation

¹ Division of Pediatric Endocrinology, Department of Pediatrics, School of Medicine, Karadeniz Technical University, Trabzon, Turkey. [email protected]

PMID: 20101896
DOI: 10.1515/jpem.2009.22.11.1087

Abstract

Rhabdomyolysis is a rare presentation of hypokalemia, although muscle weakness is a well known manifestation of marked hypokalemia. Here, we report a case of primary hyperaldosteronism due to unilateral aldosterone-producing adenoma in a 14 year-old girl who developed rhabdomyolysis following hypokalemia. To our knowledge, this is the first case of adrenocortical adenoma presenting with rhabdomyolysis in a child.

Publication types

Case Reports

MeSH terms

Adolescent
Adrenal Cortex Neoplasms / metabolism*
Adrenal Cortex Neoplasms / pathology
Adrenal Cortex Neoplasms / therapy
Adrenal Glands / diagnostic imaging
Adrenalectomy
Adrenocortical Adenoma / metabolism*
Adrenocortical Adenoma / pathology
Adrenocortical Adenoma / therapy
Aldosterone / metabolism*
Combined Modality Therapy
Female
Humans
Hypokalemia / complications
Hypokalemia / metabolism
Hypokalemia / pathology
Mineralocorticoid Receptor Antagonists / therapeutic use
Rhabdomyolysis / metabolism*
Rhabdomyolysis / pathology
Rhabdomyolysis / therapy
Spironolactone / therapeutic use
Tomography, X-Ray Computed
Treatment Outcome

Substances

Mineralocorticoid Receptor Antagonists
Spironolactone
Aldosterone