An efficient approach to quinolines via Friedländer synthesis catalyzed by cuprous triflate

Chem Pharm Bull (Tokyo). 2010 Feb;58(2):212-3. doi: 10.1248/cpb.58.212.

Abstract

A mild and efficient route for the synthesis of quinolines utilizing cuprous triflate (Cu(OTf)(2)) as a novel catalyst via Friedländer annulation in excellent yields at room temperature under solvent-free conditions was described.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Catalysis
  • Mesylates / chemistry
  • Molecular Structure
  • Quinolines / chemical synthesis*
  • Quinolines / chemistry
  • Temperature

Substances

  • Mesylates
  • Quinolines
  • copper(I) triflate