Have we understood diabetes? New tasks for diagnosis and therapy

Exp Clin Endocrinol Diabetes. 2010 Jan;118(1):1-3. doi: 10.1055/s-0029-1246117. Epub 2010 Feb 1.

Abstract

Recently published data examining the role of the metabolic syndrome and obesity in cardiovascular disease rendered surprising results. In addition, other studies revealed that there is more to diabetes therapy than lowering blood glucose, which might under certain circumstances even harm patients. In the light that we now know that "death" is as important an endpoint in diabetes as in other diseases, new tools--better than the oral glucose tolerance test--are required to identify the patients at risk, as are additional standards in individualized therapy. A critical view on old concepts is necessary.

MeSH terms

  • Blood Glucose / analysis
  • Diabetes Complications / mortality
  • Diabetes Complications / therapy
  • Diabetes Mellitus* / diagnosis
  • Diabetes Mellitus* / mortality
  • Diabetes Mellitus* / therapy
  • Glucose Tolerance Test
  • Glycated Hemoglobin / analysis
  • Humans
  • Metabolic Syndrome / mortality
  • Metabolic Syndrome / therapy
  • Overweight / mortality
  • Overweight / therapy
  • Risk Factors
  • Sedentary Behavior

Substances

  • Blood Glucose
  • Glycated Hemoglobin A
  • hemoglobin A1c protein, human