Decrease in risk of tuberculosis infection despite increase in tuberculosis among young adults in urban Vietnam

Int J Tuberc Lung Dis. 2010 Mar;14(3):289-95.

Abstract

Objective: To assess whether the increase in tuberculosis (TB) notification rates among young adults in Vietnam reflects increased transmission in the population at large.

Method: Trends of case notification rates of new smear-positive TB were calculated from routinely reported data of district TB units over the period 1996-2005. Results from repeated tuberculin surveys among children aged 6-9 years were obtained to calculate the trend in annual risk of TB infection (ARTI).

Findings: From 1996 to 2006, notification rates in the age group 15-24 years increased by 4.3% per year, and more so in highly urbanised (6.7%) than in rural districts (1.7%). The ARTI in urban districts declined from 2.4% in 1992 to 1.2% in 1998 and 0.9% in 2005. In rural districts, the ARTI increased from 0.7% in 1991 to 1.2% in 1997, and then declined to 0.9% in 2006.

Conclusion: The increase in TB notification rates among young adults in Ho Chi Minh Province is accompanied by a decrease in ARTI in children. This suggests that the trend in TB notification among young adults reflects increased rates of progression from infection to disease and/or increased transmission within this age group, rather than increased transmission in the population at large.

MeSH terms

  • Adolescent
  • Age Distribution
  • Child
  • Disease Notification / statistics & numerical data
  • Disease Progression
  • Female
  • Humans
  • Male
  • Rural Health
  • Time Factors
  • Tuberculin Test
  • Tuberculosis, Pulmonary / epidemiology*
  • Tuberculosis, Pulmonary / transmission
  • Urban Health / trends*
  • Vietnam / epidemiology
  • Young Adult