Chronic multifocal demyelinating neuropathy simulating motor neuron disease

Ital J Neurol Sci. 1991 Feb;12(1):113-8. doi: 10.1007/BF02337624.

Abstract

We describe a patient with a chronic acquired predominantly motor polyneuropathy. His clinical picture initially led to a diagnosis of lower motor neuron form of amyotrophic lateral sclerosis. However electrophysiological examination revealed multifocal, prevalently proximal, conduction blocks at sites not prone to compression. Distinguishing this unusual polyneuropathy from motor neuron diseases is critical, since the former is a potentially, treatable disorder.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Amyotrophic Lateral Sclerosis / diagnosis
  • Demyelinating Diseases / diagnosis*
  • Demyelinating Diseases / physiopathology
  • Diagnosis, Differential
  • Humans
  • Male
  • Median Nerve / physiopathology
  • Motor Neurons*
  • Neural Conduction
  • Neurologic Examination
  • Neuromuscular Diseases / diagnosis*