Globicatella sanguinis meningitis associated with human carriage

J Clin Microbiol. 2010 Apr;48(4):1491-3. doi: 10.1128/JCM.01299-09. Epub 2010 Feb 10.

Abstract

Globicatella sanguinis is a rare cause of acute meningitis. We demonstrated human carriage of Globicatella by identifying cefotaxime-resistant strains in groin and rectal specimens 9 months after invasive infection. The pathogenic strain isolated from the cerebrospinal fluid and the carriage strains were accurately identified by sodA gene sequence analysis.

Publication types

  • Case Reports

MeSH terms

  • Aerococcaceae / classification
  • Aerococcaceae / genetics
  • Aerococcaceae / isolation & purification*
  • Anti-Bacterial Agents / pharmacology
  • Bacterial Proteins / genetics
  • Bacterial Typing Techniques
  • Carrier State / microbiology*
  • Cefotaxime / pharmacology
  • Cerebrospinal Fluid / microbiology
  • DNA, Bacterial / chemistry
  • DNA, Bacterial / genetics
  • Female
  • Genotype
  • Gram-Positive Bacterial Infections / diagnosis*
  • Gram-Positive Bacterial Infections / microbiology
  • Groin / microbiology
  • Humans
  • Meningitis, Bacterial / diagnosis*
  • Meningitis, Bacterial / microbiology
  • Middle Aged
  • Molecular Sequence Data
  • Rectum / microbiology
  • Sequence Analysis, DNA
  • Superoxide Dismutase / genetics
  • beta-Lactam Resistance

Substances

  • Anti-Bacterial Agents
  • Bacterial Proteins
  • DNA, Bacterial
  • SodA protein, Bacteria
  • Superoxide Dismutase
  • Cefotaxime

Associated data

  • GENBANK/EU649715
  • GENBANK/EU649716
  • GENBANK/HDP50220
  • GENBANK/HDP60616
  • GENBANK/HDP60617