Primary cutaneous Ewing's sarcoma/primitive neuroectodermal tumor manifesting numerous small and huge ulcerated masses: its complete remission by chemotherapy and magnetic resonance imaging findings

Skeletal Radiol. 2010 Jun;39(6):595-600. doi: 10.1007/s00256-009-0872-x. Epub 2010 Feb 12.

Abstract

Extraskeletal Ewing's sarcoma (ES) and primitive neuroectodermal tumor (PNET) are widely regarded as clinically and histologically identical tumors which consist of small blue round cells. Extraskeletal ESs/PNETs usually occur in the deep soft tissues of the paraspinal region, chest wall, or lower extremities. However, superficially located cases, so-called cutaneous ESs/PNETs, are exceedingly rare, and the vast majority of the reported cases present as a single small mass. We present magnetic resonance imaging (MRI) findings and clinical course of a unique case of primary cutaneous ES/PNET presenting as numerous huge masses with severe ulceration on them.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Agents / administration & dosage*
  • Humans
  • Magnetic Resonance Imaging / methods*
  • Male
  • Middle Aged
  • Neoplasms, Multiple Primary / complications
  • Neoplasms, Multiple Primary / diagnosis*
  • Neoplasms, Multiple Primary / drug therapy
  • Neuroectodermal Tumors / complications
  • Neuroectodermal Tumors / diagnosis*
  • Neuroectodermal Tumors / drug therapy
  • Sarcoma, Ewing / complications
  • Sarcoma, Ewing / diagnosis*
  • Sarcoma, Ewing / drug therapy
  • Skin Neoplasms / complications
  • Skin Neoplasms / diagnosis*
  • Skin Neoplasms / drug therapy
  • Treatment Outcome
  • Ulcer / diagnosis*
  • Ulcer / etiology
  • Ulcer / prevention & control

Substances

  • Antineoplastic Agents