CD4+ T cell plasticity-Th2 cells join the crowd

Jinfang Zhu; William E Paul

doi:10.1016/j.immuni.2010.01.001

CD4+ T cell plasticity-Th2 cells join the crowd

Immunity. 2010 Jan 29;32(1):11-3. doi: 10.1016/j.immuni.2010.01.001.

Authors

Jinfang Zhu¹, William E Paul

Affiliation

¹ Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA. [email protected]

Abstract

In this issue of Immunity, Hegazy et al. (2010) report that in response to lymphocytic choriomeningitis virus (LCMV) infection, fully differentiated virus-specific Th2 cells can be reprogrammed into GATA-3(+)T-bet(+) cells capable of producing both interleukin-4 and interferon-gamma.

Publication types

Review

MeSH terms

Animals
Cell Differentiation / immunology
Humans
Lymphocyte Activation / immunology
Th2 Cells / cytology
Th2 Cells / immunology*

Abstract

Publication types

MeSH terms

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