The association between the harm avoidance subscale of the Tridimensional Personality Questionnaire and serotonin transporter availability in the brainstem of male volunteers

I Ting Wu; I Hui Lee; Tzung Lieh Yeh; Kao Ching Chen; Po See Chen; Wei Jen Yao; Yen Kuang Yang

doi:10.1016/j.pscychresns.2009.10.005

The association between the harm avoidance subscale of the Tridimensional Personality Questionnaire and serotonin transporter availability in the brainstem of male volunteers

Psychiatry Res. 2010 Mar 30;181(3):241-4. doi: 10.1016/j.pscychresns.2009.10.005. Epub 2010 Feb 11.

Authors

I Ting Wu¹, I Hui Lee, Tzung Lieh Yeh, Kao Ching Chen, Po See Chen, Wei Jen Yao, Yen Kuang Yang

Affiliation

¹ Department of Psychiatry, National Cheng Kung University Hospital, 138 Sheng Li Road, Tainan 70428, Taiwan.

PMID: 20153151
DOI: 10.1016/j.pscychresns.2009.10.005

Abstract

The relationship between harm avoidance scores of the Tridimensional Personality Questionnaire and serotonin transporter availability, as approximated using single photon emission computed tomography with [(123)I] ADAM, was examined. Our results showed a significant negative correlation between the harm avoidance total score, as well as the asthenia subscore, and serotonin transporter availability, particularly in males.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adult
Benzyl Alcohols / metabolism
Brain Stem / diagnostic imaging
Brain Stem / metabolism*
Female
Harm Reduction / physiology*
Humans
Male
Middle Aged
Personality / genetics*
Personality Inventory
Polymorphism, Genetic / genetics
Serotonin Plasma Membrane Transport Proteins / genetics*
Sex Characteristics*
Statistics as Topic
Sulfides / metabolism
Surveys and Questionnaires
Tomography, Emission-Computed, Single-Photon / methods
Young Adult

Substances

5-iodo-2-((2-((methylamino)methyl)phenyl)thio)benzyl alcohol
Benzyl Alcohols
Serotonin Plasma Membrane Transport Proteins
Sulfides