Long-term immunity after two doses of inactivated hepatitis A vaccine, in Argentinean children

Pediatr Infect Dis J. 2010 Jun;29(6):568-70. doi: 10.1097/INF.0b013e3181d57a85.

Abstract

We examined long-term anti-hepatitis A virus antibody persistence in Argentinean children 10 years after the initial study in which they received 2 doses of inactivated hepatitis A vaccine (Avaxim 80U). Of the 111 children, 48 from the initial trial were enrolled. Of 48, 47 (97.9%) participants had serum anti-hepatitis A virus antibody titers > or =20 mIU/mL, with the geometric mean concentration of 390.91 (+/-370.14) mIU/mL; (95% confidence interval, 282.2-499.5 mIU/mL), range, 36 to 1860.

MeSH terms

  • Adolescent
  • Argentina / epidemiology
  • Chi-Square Distribution
  • Child
  • Female
  • Follow-Up Studies
  • Hepatitis A / epidemiology
  • Hepatitis A / immunology
  • Hepatitis A / prevention & control*
  • Hepatitis A Antibodies / blood
  • Hepatitis A Vaccines / administration & dosage*
  • Hepatitis A Vaccines / immunology*
  • Humans
  • Immunization Schedule
  • Male
  • Statistics, Nonparametric
  • Vaccines, Inactivated / administration & dosage
  • Vaccines, Inactivated / immunology

Substances

  • Hepatitis A Antibodies
  • Hepatitis A Vaccines
  • Vaccines, Inactivated