[Type 2 diabetes mellitus associated with pancreatic and renal malformations]

J-P Le Berre; C Bellanné-Chantelot; L Bordier; C Garcia; O Dupuy; H Mayaudon; B Bauduceau

doi:10.1016/j.revmed.2009.04.008

[Type 2 diabetes mellitus associated with pancreatic and renal malformations]

Rev Med Interne. 2010 Jun;31(6):e5-6. doi: 10.1016/j.revmed.2009.04.008. Epub 2010 Mar 4.

[Article in French]

Authors

J-P Le Berre¹, C Bellanné-Chantelot, L Bordier, C Garcia, O Dupuy, H Mayaudon, B Bauduceau

Affiliation

¹ Service d'endocrinologie, hôpital d'instruction des armées Bégin, 69, avenue de Paris, 94160 Saint-Mandé, France. [email protected]

PMID: 20206420
DOI: 10.1016/j.revmed.2009.04.008

Abstract

A 55-year-old woman presented with a recent diabetes mellitus associated with pancreatic and renal malformations. This atypical diabetes raised the possibility of maturity onset diabetes of the young (MODY) and a genetic research was performed. These malformations led to MODY5 diagnosis that was confirmed by the presence of HNF1beta gene mutation.

Publication types

Case Reports
English Abstract

MeSH terms

Biomarkers / metabolism
Diabetes Mellitus, Type 2 / genetics*
Female
Genetic Counseling
Hepatocyte Nuclear Factor 1-beta / genetics*
Humans
Kidney / abnormalities*
Middle Aged
Mutation
Pancreas / abnormalities*
Phenotype

Substances

Biomarkers
Hepatocyte Nuclear Factor 1-beta