[Neurogenic tumors of the mediastinum in adults]

Rev Pneumol Clin. 2010 Feb;66(1):81-94. doi: 10.1016/j.pneumo.2009.12.010. Epub 2010 Feb 19.
[Article in French]

Abstract

In adults, mediastinal neurogenic tumours constitute the third group of mediastinal tumours, after thymomas and lymphomas. If the group of neurogenic tumour is frequent, each type of tumour is relatively unusual in everyday's clinic. Among them, nerve sheath tumours are the more frequent, followed by tumour of the autonomic system. Askin tumour remains uncommon. Treatment of this tumour requires complete preoperative work-up, including standard radiography, CT-scan, MRI, and sometimes nuclear imaging. In most cases, the treatment is based on surgical resection, and may be associated with radiotherapy or chemotherapy in case of malignant tumour or incomplete resection. Better understanding of these tumours, including their molecular abnormalities, may lead to new changes in their classifications, and to their management.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Adult
  • Child
  • Ganglia, Autonomic* / pathology
  • Ganglia, Autonomic* / surgery
  • Ganglioneuroblastoma / classification
  • Ganglioneuroblastoma / pathology
  • Ganglioneuroblastoma / surgery*
  • Ganglioneuroma / classification
  • Ganglioneuroma / pathology
  • Ganglioneuroma / surgery*
  • Humans
  • Mediastinal Neoplasms / classification
  • Mediastinal Neoplasms / pathology
  • Mediastinal Neoplasms / surgery*
  • Nerve Sheath Neoplasms / classification
  • Nerve Sheath Neoplasms / pathology
  • Nerve Sheath Neoplasms / surgery*
  • Paraganglioma / classification
  • Paraganglioma / pathology
  • Paraganglioma / surgery*
  • Peripheral Nervous System Neoplasms / classification
  • Peripheral Nervous System Neoplasms / pathology
  • Peripheral Nervous System Neoplasms / surgery*
  • Prognosis
  • Thoracic Surgery, Video-Assisted
  • Tomography, X-Ray Computed