Serum levels of 25-hydroxyvitamin D in mothers of Swedish and of Somali origin who have children with and without autism

Acta Paediatr. 2010 May;99(5):743-747. doi: 10.1111/j.1651-2227.2010.01755.x. Epub 2010 Mar 5.

Abstract

Aim: To analyse serum levels of 25-hydroxyvitamin D in mothers of Somali origin and those of Swedish origin who have children with and without autism as there is a growing evidence that low vitamin D impacts adversely on brain development.

Method: Four groups of mothers were invited to participate; 20 with Somali origin with at least one child with autism, 20 with Somali origin without a child with autism, 20 of Swedish origin with at least one child with autism and 20 with Swedish origin without a child with autism. Two blood samples were collected from each individual; during autumn and spring.

Results: Between 12 and 17 mothers from the different groups accepted to participate, both groups of mothers of Somali origin had significantly lower values of 25-hydroxyvitamin D compared with Swedish mothers. The difference of 25-hydroxyvitamin D between mothers of Somali origin with and without a child with autism was not significant.

Conclusion: Our findings of low vitamin D levels in Somali women entail considerable consequences in a public health perspective. The observed tendency, i.e. the lowest values in mothers of Somali origin with a child with autism was in the predicted direction, supporting the need for further research of vitamin D levels in larger samples of Somali mothers of children with and without autism.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Autistic Disorder / ethnology*
  • Autistic Disorder / etiology
  • Case-Control Studies
  • Child, Preschool
  • Female
  • Humans
  • Maternal Nutritional Physiological Phenomena*
  • Prevalence
  • Seasons
  • Somalia / ethnology
  • Sweden / epidemiology
  • Vitamin D / analogs & derivatives*
  • Vitamin D / blood
  • Vitamin D Deficiency / complications
  • Vitamin D Deficiency / ethnology*

Substances

  • Vitamin D
  • 25-hydroxyvitamin D