Osteopontin in diabetic nephropathy: signpost or road?

Kidney Int. 2010 Apr;77(7):565-6. doi: 10.1038/ki.2009.515.

Abstract

Defining the molecular pathogenesis of diabetic nephropathy remains a huge challenge to the medical research community. Recent studies of knockout mice have provided new insights into the role of osteopontin in the pathogenesis of diabetic nephropathy.

Publication types

  • Comment

MeSH terms

  • Albuminuria / drug therapy
  • Albuminuria / etiology
  • Animals
  • Diabetes Mellitus, Experimental / complications
  • Diabetes Mellitus, Experimental / drug therapy
  • Diabetes Mellitus, Experimental / metabolism
  • Diabetic Nephropathies / complications
  • Diabetic Nephropathies / drug therapy
  • Diabetic Nephropathies / metabolism*
  • Mice
  • Osteopontin / metabolism*
  • Thiazolidinediones / therapeutic use

Substances

  • Thiazolidinediones
  • Osteopontin