Effects of unilateral dysfunction of the inferior vestibular nerve system on postural stability

Clin Neurophysiol. 2010 Aug;121(8):1279-84. doi: 10.1016/j.clinph.2010.02.149. Epub 2010 Mar 15.

Abstract

Objective: To investigate whether disorders of the inferior vestibular nerve (IVN) system affect postural stability.

Method: Two-legged stance tasks were performed by patients with unilateral peripheral vestibulopathy (n=108) in four conditions: eyes open or eyes closed, with or without foam rubber. We examined six parameters: the velocity of movement of the center of pressure and the envelopment area determined by tracing the movement in the eyes closed/foam rubber condition, Romberg's ratio of velocity and area with foam rubber, and the foam ratios (ratios of a measured parameter with to without the foam rubber) of velocity and area with eyes closed.

Results: The values of all six parameters were significantly higher in patients with unilateral vestibulopathy whose cervical vestibular evoked myogenic potentials (cVEMPs) were abnormal compared with healthy controls (p<0.01). Four of the six parameters showed significantly higher values (p<0.05) in patients with unilateral abnormal cVEMPs in the presence of normal caloric responses compared with the controls.

Conclusions: Foam posturography is useful for making a preliminary assessment of unilateral vestibulopathy with abnormal cVEMPs. Selective damage of the unilateral IVN system could affect postural stability.

Significance: We proved the influence of the disorder of the IVN system on postural stability.

MeSH terms

  • Adult
  • Aged
  • Area Under Curve
  • Electromyography
  • Evoked Potentials / physiology
  • Female
  • Functional Laterality / physiology*
  • Humans
  • Male
  • Middle Aged
  • Postural Balance / physiology*
  • Proprioception / physiology
  • Signal Processing, Computer-Assisted
  • Vestibular Function Tests
  • Vestibular Nerve / physiopathology*
  • Vestibulocochlear Nerve Diseases / physiopathology*