Efficacy of ivabradine in a case of inappropriate sinus tachycardia and ventricular dysfunction

Antonella Sette; Annamaria Martino; Ernesto Lioy; Leonardo Calò

doi:10.1111/j.1540-8167.2009.01699.x

Efficacy of ivabradine in a case of inappropriate sinus tachycardia and ventricular dysfunction

J Cardiovasc Electrophysiol. 2010 Jul;21(7):815-7. doi: 10.1111/j.1540-8167.2009.01699.x. Epub 2010 Mar 5.

Authors

Antonella Sette¹, Annamaria Martino, Ernesto Lioy, Leonardo Calò

Affiliation

¹ Cardiology Department, Policlinico Casilino, ASL Rome B, Italy. [email protected]

PMID: 20233274
DOI: 10.1111/j.1540-8167.2009.01699.x

Abstract

We present a case of a 49-year-old man with inappropriate sinus tachycardia and ventricular dysfunction. The conventional treatment (ace-inhibitor and beta-blockers) was not well tolerated by the patient, so Ivabradine, a specific inhibitor of If current in the sinus node, was started. After 3 months of using this medication, we observed an improvement of ejection fraction and quality of life.

Publication types

Case Reports

MeSH terms

Anti-Arrhythmia Agents / therapeutic use*
Benzazepines / therapeutic use*
Electrocardiography
Heart Rate / drug effects
Humans
Ivabradine
Male
Middle Aged
Quality of Life
Stroke Volume / drug effects
Tachycardia, Sinus / complications
Tachycardia, Sinus / drug therapy*
Tachycardia, Sinus / physiopathology
Time Factors
Treatment Outcome
Ventricular Dysfunction, Left / drug therapy*
Ventricular Dysfunction, Left / etiology
Ventricular Dysfunction, Left / physiopathology
Ventricular Function, Left / drug effects

Substances

Anti-Arrhythmia Agents
Benzazepines
Ivabradine