Abstract
The solution structure of (+)-spongistatin 1 (1) has been determined via 1- and 2-D NMR techniques in conjunction with extensive in silico conformational analysis to comprise a mixture of 4 major rapidly interconverting conformational families.
Publication types
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Research Support, N.I.H., Extramural
MeSH terms
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Dimethyl Sulfoxide / chemistry*
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Macrolides / chemistry*
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Magnetic Resonance Spectroscopy
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Models, Molecular
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Molecular Conformation
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Solutions
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Stereoisomerism
Substances
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Macrolides
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Solutions
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spongistatin 1
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Dimethyl Sulfoxide