Transient visual loss triggered by scuba diving in a patient with a petrous epidermoid and combined thrombotic risk factors

Pathophysiol Haemost Thromb. 2007;36(6):311-4. doi: 10.1159/000297738. Epub 2010 Mar 17.

Abstract

A 25-year-old woman who developed transient neurological abnormalities after scuba diving is reported. The subsequent day she experienced transient left-side monocular blindness. Arterial ocular occlusion in apparently healthy young women is unusual, and a search for the cause of this devastating vascular event is mandatory. Occlusion of the left branch retinal artery, total occlusion of the left internal carotid artery, and a petrous apex epidermoid were found, together with a shortened prothrombin time (INR: 0.73), a slightly elevated serum cholesterol level (6.1 mmol/l) and combined thrombophilia (elevated FVIIIC plus type 2 sticky platelet syndrome). This case underlines the complex mechanism of thromboembolic diseases, and the importance of the acquired trigger (in the present case scuba diving) in addition to the long-term anatomical and biochemical risk factors.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Amaurosis Fugax / epidemiology
  • Amaurosis Fugax / etiology*
  • Amaurosis Fugax / pathology
  • Bone Diseases / complications*
  • Bone Diseases / epidemiology
  • Bone Diseases / pathology
  • Carotid Artery Thrombosis / epidemiology
  • Carotid Artery Thrombosis / etiology*
  • Carotid Artery Thrombosis / pathology
  • Carotid Artery, Internal
  • Cholesterol / blood
  • Diving / adverse effects*
  • Epidermal Cyst / complications*
  • Epidermal Cyst / epidemiology
  • Epidermal Cyst / pathology
  • Factor VIII / metabolism
  • Female
  • Humans
  • Magnetic Resonance Angiography
  • Magnetic Resonance Imaging
  • Petrous Bone
  • Prothrombin Time
  • Retinal Artery
  • Risk Factors
  • Thrombophilia / complications*
  • Thrombophilia / epidemiology

Substances

  • Factor VIII
  • Cholesterol