Resurgence of yellow fever epidemics in Côted'Ivoire remains a major problem of public health. To describe this disease through the early alarm system of National Institute of Public Hygiene (NIPH) is convenient to us. This is a cross-sectional study with descriptive aiming, which proceeded with epidemiological surveillance service of NIPH. The data were collected over 7 years (from 2001 to 2007), starting from the cards of notification, reports, and registers of the service. The main findings of our study are that: 1) we listed 1468 suspect cases including 41 confirmed and the lethality rate was 17.07% among the confirmed cases; 2) most cases of yellow fever were recorded between the years 2001 and 2007; 3) confirmed cases of yellow fever were above 15 years old in 83% of cases. This could be explained by absence of immunization during this age period; 4) recrudescence of cases was observed during the rainy season (June-July and September-October) and the principal vector was Aedes aegypti; 5) data analysis revealed a mean level of 79% for completude and 57%for promptitude of notification; these rates are inferior to WHO norms and; 6) average time of vaccine response post-epidemic was 31 days. Late response is due to difficulties in supplying vaccines. Reinforcement of epidemiological surveillance, prevention by mass immunization, and measurements of hygiene and cleansing are essential to slow down the evolution of this disease.