Health economics of use fluoroquinolones to treat patients with community-acquired pneumonia

Am J Med. 2010 Apr;123(4 Suppl):S39-46. doi: 10.1016/j.amjmed.2010.02.005.

Abstract

Respiratory diseases account for approximately 10% of all hospital admissions in the United States. Pneumonia constitutes 35% of these cases, with an average length of stay (LOS) of 5.1 days. It is estimated that $8.4 billion to $10 billion of all annual US hospital expenditures are attributable to community-acquired pneumonia (CAP). As such, medical decisions, including empiric antibiotic choice, potentially exert an impact on hospital LOS and associated costs. In this review, we focus on the empiric antibiotic choices and associated costs of treatment for hospitalized patients with CAP, focusing on the use of fluoroquinolone therapy as recommended by the CAP guidelines.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Administration, Oral
  • Anti-Bacterial Agents / administration & dosage
  • Anti-Bacterial Agents / economics*
  • Anti-Bacterial Agents / therapeutic use*
  • Community-Acquired Infections / drug therapy
  • Community-Acquired Infections / economics
  • Drug Costs*
  • Drug Therapy, Combination
  • Fluoroquinolones / administration & dosage
  • Fluoroquinolones / economics*
  • Fluoroquinolones / therapeutic use*
  • Humans
  • Infusions, Intravenous
  • Length of Stay / economics
  • Macrolides / economics
  • Macrolides / therapeutic use
  • Pneumonia / drug therapy*
  • Pneumonia / economics*
  • Severity of Illness Index
  • Treatment Outcome
  • United States
  • beta-Lactams / economics
  • beta-Lactams / therapeutic use

Substances

  • Anti-Bacterial Agents
  • Fluoroquinolones
  • Macrolides
  • beta-Lactams