Single-nucleotide evolutionary constraint scores highlight disease-causing mutations

Nat Methods. 2010 Apr;7(4):250-1. doi: 10.1038/nmeth0410-250.
No abstract available

Publication types

  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Evolution, Molecular*
  • Genetic Predisposition to Disease
  • Genetic Variation
  • Genome, Human
  • Humans
  • Models, Genetic*
  • Mutation*