Intravenous zanamivir for patients with pneumonitis due to pandemic (H1N1) 2009 influenza virus

Clin Infect Dis. 2010 May 1;50(9):1249-51. doi: 10.1086/651604.

Abstract

We report on 2 critically ill patients with pneumonitis and acute respiratory distress syndrome due to pandemic (H1N1) 2009 influenza A virus who were treated with intravenous zanamivir and had favorable clinical outcomes. Zanamivir given intravenously may be a therapeutic option in patients with critical illness and mechanical ventilation.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Antiviral Agents / administration & dosage
  • Antiviral Agents / therapeutic use*
  • Critical Illness
  • Humans
  • Influenza A Virus, H1N1 Subtype / isolation & purification*
  • Influenza, Human / complications*
  • Influenza, Human / drug therapy*
  • Influenza, Human / virology
  • Injections, Intravenous
  • Male
  • Middle Aged
  • Pneumonia / drug therapy*
  • Respiratory Distress Syndrome / drug therapy
  • Treatment Outcome
  • Zanamivir / administration & dosage
  • Zanamivir / therapeutic use*

Substances

  • Antiviral Agents
  • Zanamivir