Pulmonary amyloidosis in Sjögren's syndrome: a rare diagnosis for nodular lung lesions

Int J Rheum Dis. 2009 Dec;12(4):358-60. doi: 10.1111/j.1756-185X.2009.01436.x.

Abstract

Lung involvement in Sjögren's syndrome (SS) can affect trachea, bronchus, small airways, pleura and may cause interstitial lung injury. It may also be associated with malignancies, particularly non-Hodgkin's lymphoma, which is a well-recognized complication of this disease. Here we describe the occurrence of localized amyloidosis presenting as pulmonary nodules in a patient with newly diagnosed SS. We highlight this rare occurrence as a diagnostic possibility that should be considered in the evaluation of pulmonary involvement in this disease.

Publication types

  • Case Reports

MeSH terms

  • Amyloid / chemistry
  • Amyloidosis / complications
  • Amyloidosis / diagnosis*
  • Amyloidosis / drug therapy
  • Antirheumatic Agents / therapeutic use
  • Azathioprine / therapeutic use
  • Coloring Agents / chemistry
  • Congo Red / chemistry
  • Drug Therapy, Combination
  • Female
  • Glucocorticoids / therapeutic use
  • Humans
  • Hydroxychloroquine / therapeutic use
  • Lung Diseases / complications
  • Lung Diseases / diagnosis*
  • Lung Diseases / drug therapy
  • Middle Aged
  • Prednisone / therapeutic use
  • Sjogren's Syndrome / complications
  • Sjogren's Syndrome / diagnosis*
  • Sjogren's Syndrome / drug therapy
  • Treatment Outcome

Substances

  • Amyloid
  • Antirheumatic Agents
  • Coloring Agents
  • Glucocorticoids
  • Congo Red
  • Hydroxychloroquine
  • Azathioprine
  • Prednisone