Matrix metalloproteinases are elevated in the urine of patients with endometriosis

Fertil Steril. 2010 Nov;94(6):2343-6. doi: 10.1016/j.fertnstert.2010.02.040. Epub 2010 Apr 7.

Abstract

In a prospective, blinded, longitudinal study MMP-2, MMP-9, and MMP-9/neutrophil gelatinase-associated lipocalin were significantly more likely to be detected in the urine of patients with endometriosis than in controls.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Biomarkers / metabolism
  • Biomarkers / urine
  • Case-Control Studies
  • Endometriosis / enzymology
  • Endometriosis / metabolism
  • Endometriosis / urine*
  • Female
  • Humans
  • Matrix Metalloproteinase 2 / urine
  • Matrix Metalloproteinase 9 / urine
  • Matrix Metalloproteinases / metabolism
  • Matrix Metalloproteinases / urine*
  • Up-Regulation
  • Uterine Diseases / enzymology
  • Uterine Diseases / metabolism
  • Uterine Diseases / urine*

Substances

  • Biomarkers
  • Matrix Metalloproteinases
  • Matrix Metalloproteinase 2
  • Matrix Metalloproteinase 9