HIV-1 subtype C transmission network: the phylogenetic reconstruction strongly supports the epidemiological data

J Clin Virol. 2010 Jul;48(3):212-4. doi: 10.1016/j.jcv.2010.03.021. Epub 2010 Apr 18.

Abstract

The sequence and times of the transmission events was reported after a hospital accident by a phylodynamic reconstruction of transmission network among four subjects. The dated tree allowed to date the transmission events with good approximation, the time point and direction of each transmission, estimated on the basis of the phylogeny, and agreed with the presumptive time of infection on the basis of clinical history-taking.

Publication types

  • Case Reports

MeSH terms

  • Cluster Analysis
  • Female
  • Genotype
  • HIV Infections / epidemiology*
  • HIV Infections / transmission
  • HIV Infections / virology*
  • HIV-1 / classification*
  • HIV-1 / genetics*
  • HIV-1 / isolation & purification
  • Humans
  • Infant, Newborn
  • Molecular Epidemiology
  • Phylogeny*
  • Polymorphism, Genetic*
  • Sequence Analysis, DNA
  • pol Gene Products, Human Immunodeficiency Virus / genetics

Substances

  • pol Gene Products, Human Immunodeficiency Virus