The authors report a rare case of primary mucinous eccrine adenocarcinoma of the skin initially diagnosed as metastatic adenocarcinoma and treated with local excision and adjuvant radiotherapy in another center. The tumor reoccurred in the left axilla 2.5 years later after the initial treatment. Diagnosis in our center was primary cutaneous eccrine mucinous adenocarcinoma. We present the clinical, histological, and immunohistochemical features of this rare tumor in the light of the searched literature.